Some are convinced letting them die all the way is correct. I have never done this. I always train vigorous energy upward in compromised situations. Indoor is compromise all the way. Just the same, I see great results (from others) from letting them wither and removing to prevent mold.
My first thought was for maximizing harvest, so, I would prune. But, your approach is different, so it is best to ask someone with at least a little experience,