First, you will need a vented enclosure for the drivers. They get quite hot. When I looked into it, they were quite expensive, like a couple hundred $$. I ended up making a wood frame and mounted the drivers to that with the wiring tucked nicely behind it.
16-guage wire should get you about 10’ before the voltage drop becomes an issue.
The meqnwell HLG drivers have a lot of safety features like over temp, over power, etc. That being said, my lights are on a separate circuit breaker in the subpanel, and the plug is a GFCI plug for added safety.