Well, that device is interesting mostly for the form factor and the keyfob access.
From what it appears, they are trying to control what happens with physical access to the machine. Much of this can be managed by ensuring that your location is physically secure in the first place. Have an untrustworthy “friend” hanging around near your equipment? Your physical security is flawed by default. The more significant problem from a security standpoint will be the software and firmware. Hook this thing up to the network and a software or firmware vulnerability could render all that fancy intrusion detection hardware useless.
If you have someone who bypasses your physical security and is looking for something specific on your computer, has the knowledge to hack into the hardware / bootloader, you probably have some significant issues to deal with. They note PCIe security, for instance. This is a feature built into modern processors (deep in the firmware/bootloader/OS) and it is up to the bootloader to set the appropriate security bits to prevent what amounts to “core debug” access. But, even if this subsystem is set-up insecurely, anyone going through the trouble to use this attack vector is one serious individual indeed.
A regular PC with appropriate external firewalls, internal firewall, software protection tools, firewalled subnets, appropriate data encryption. Add physical security and you’ll have a fairly safe system. Take it off the network if your are extra paranoid (air gap).
Of course, layering security is always a good idea and perhaps this device could be considered another layer in your overall scheme. And, if you have unique needs such as travelling across borders with this thing in tow, maybe this type of intrusion protection could be of some use against the casual hacker / theft. Nothing wrong with having one of these but I think the benefits of having the features of this device will only be useful for rather unique situations.