I assume your referring to open field cultivation e.g. no greenhouse, hot house or covered area.
First I would suggest checking out your specific local weather averages for each month. Knowing your last frost, first frost, precipitation, humidity and temperature throughout your growing season is important. Then base your strain selection on that.
Looking at missouri as a whole, it seems you have a very humid, hot and rainy summer. with fall having somewhat cold nights, sporadic precipitation and mild humidity.
If you go fully auto, I’d try and find something tropical/subtropical sativa based. Something that can handle flowering in a warm wet humid summer. Maybe auto zamaldelica, auto malawi. You’ll want to sprout these directly into 5gal pots as they don’t respond well to repotting.
You could go with semi autos. Pre veging indoors is discouraged on these. Unless you really know what your doing, they sould be planted directly outdoors. Maybe a timewarp cross, purple pineberry, freezeland, erdpurt. there is a decent amount of options here but they can be somewhat difficult to source.
If you want to go photo dependent, you’ll want to select something that can handle your fall weather 50f-40f nights mild rain and humidity. You would probably do well with bangi haze, nepalese jam. Something holding nepali or north indian genetics is a good bet. Those high altitude sativas are known to handle cold and moisture well.
As for medium, id suggest going with what you are use too. Ive seen some real nice outdoor coco runs. You probably have a pile of old coco root balls handy. Just break them up while pulling out the larger root chunks and add a bit of enzyme to break down the smaller root bits. Plus the increased speed of growth with coco is nice.