It will depend mostly on the whole procedure of selection than happend before this operation. Basically if you prepare a line for that.
In this specific case it can value the complications and the difficult stabilization to do after. The level of cannabinoids don’t stay in offspring like the treated plants, but the footprint is enough big (when prepared) to be valuable in some circumstances.
To get out from the “spray and prey”, you absolutely need to known your line’s segregations equilibriums by heart and really breed it for that. The mess created by polyploids is big, so you need an epurated line with little to no variation to master the outcome. But it can be advantageous too if you need to known, experimentally, the genetic potential of the potency of a gived line. If the average of the offspring finish below the reference or worst, you known than you pushed allready the line in its genetic limits.
Can be usefull also to study different kind of reccurent mutations in cannabis : variegations, “siamese twins”, certain types of hermaphrodism (gynomonoecy mostly), colors also …