Pancreatic is hard. Yes, CBD will dissolve in any lipid.
There is evidence CBD is more effective with at least some THC. I wouldn’t rely on just CBD, maybe a blend of traditional Cannabis RSO extract with some extra CBD for good measure, plus THC is what really helps with appetite and maintaining good spirits/pain relief/nausea relief.
From my limited experience…it can be difficult to get older folks to actually stick to the dosage schedule. I got my grandma some edibles and she only took them for 2 days because it wasn’t “working” like OK no problem we just need to increase dosage and stick to it but many still feel weird taking “drugs”. Ive had family members with terminal cancer who didn’t take their pain meds because they don’t want to be “addicted”. Definitely a psychological aspect to it.