Best number of plants for my setup?

Old thread, but i have question
I have 4x4 area
I see that the number of plants is not relevant.
And what about well-developed flowers?
Let’s say that the entire canopy is filled with the main buds and that all the lower growth is removed.
I am planning four plants.
On how many equal buds would you train each plant to fill a 4x4 space?

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