i had the same thoughts on strain-hunting at least, if not hybridizing. i.e. my Durban has some magic in it, but it's a bitch to grow.
And it could use some structural beefing-up...hemp-ification. heh.
There's no question in my mind about this. If the body makes THC, then it's gotta lot to do with all the other stuff, including(especially?) THCvariants.
Kevin Jodrey is where I think I first heard it put that smoking cannabis(and tobacco or crack for the matter), is essentially 'aromatherapy'. Like a lavender thingamabob or eucalyptus doodad or whatever. Perfume department at Macys made me ill in seconds...so there's your evil-- i'm pretty allergic to it.
the strain i really took to when i started smoking was called 'the cave'...i have no idea what it was, probably BC genetics, from an east-coast cat transplanted to CA. the legend was it was grown by gnomes under mt. tamalpais. if so, they were masters at hydro & flushing. the skunk/pine combo was enough to make a dude by extra carbon filters. maybe even a dead skunk for the front yard to fuck with people.