Growing out highly different strains could allow you to come out with two or three different unique lines if you have a clear idea of where you’re going. There should also be a high chance of hybrid vigor if you properly line-breed the hybrid, but that’s not important right now. The most important fact right now is that Mendelian genetics assumes you have an infinite population. Unless you can purchase a few hundred seeds direct from the breeders, – which is by far the best option if that is possible – I have two suggestions.
First, If you inbreed each line once to multiply the seeds you have to choose from, you will automatically increase your chance of producing a successful cross by decreasing the chance of breeding with any shitty parents. Growing out two generations of each of these lines will give you a better idea of what the cream of the crop looks like, too.
Second, When you cross the two parental lines together without having already vetted their combining ability, using multiple males of Line-A to pollinate the females of Line-B and multiple males from Line-B to pollinate the females from Line-A will increase your chance of success compared to one-on-one crosses.
TL:DR = Plants are lottery tickets, more plants to choose from increases the chance of a jackpot