Heh, speaking of, check out this old ad from High Times back in 79!
When I grew out JOTI’s Afghani line, as well as AKBB’s 89NL line, I saw heavy mutations, tons of whorled phyllotaxy, things that looked like two different plant structures trying to grow in the same body, etc. A lot of things that make me think Colchicine was used in the past. I doubt that’s the only line it would have happened to too. Especially considering ads like this, way back then.