Sure.
There’s an old grower saying “your favorite plant or expected keeper will change 3 times during a run, once in veg, once in flower and again in the pipe”.
If you’re planning to breed, I’d surmise it would change a 4th time. First let’s define what’s a good breeder plant. A good breeder plant would be one that is homozygous for a certain trait or, if you’re lucky, traits.
Let me add to the aforementioned exemple. You grow 50 plants of a certain cross/line, pick the best 10 females, smoke test them and keep the better 5. You would then self each of the 5 to find out which passes chosen traits more consistently. Usually the difference will be marked and top around 50% of progeny showing the trait/s. Other families that don’t make the cut could be in the low 10s in percentage.
This plant. The one that passes chosen traits consistently is a good breeder plant. It is not necessarily your first choice to smoke. Could be 4/5 for smoke but 1/5 for strong babies.
Look at Beyoncé’s parents.
Selfing is said to be ~3x more aggressive because it relies on a single input and will double up on genes to show what’s what, kicking lonely genes to the curb in the process.
Stabilizing a line involves zeroing in on a certain phenotype, or, bettering the mean of the line while taming the extremes, giving rise to more of the same but statistically less of stellar, outlier specimens.
A line can be worked to the point where it’s accumulating more negatives in favor of a couple traits and can become “too inbred” “close to the breaking point” and thus be better used in a cross.
Rinse repeat…
If you look at how quality auto are bred it will show you how DNA Legos are put together and shine light on many important breeding principles.
From the ground up
Auto x photo = fast
Fast x fast = 25% of them autos
Auto x auto = 100% auto
Congratulations, you have an auto. But it’s crap
So you rinse and repeat.
You cross your auto to a photo breeder cut to infuse your auto with.
Your auto x breeder cut of choice (z smell) = fast
Fast z crossed to fast z = auto z
Auto z has the smell, cool
Cross auto z with a photo breeder cut with superb high
Auto z x photo superb high = fast z superb
Fast z superb x fast z superb = auto z superb
Each step requiring selection
Block by block
Piece by piece